Research profile
Nicotinamide N-methyltransferase inhibition
Preclinical evidence
What it is and why it is studied
5-Amino-1MQ is studied as an inhibitor of nicotinamide N-methyltransferase, or NNMT. Researchers investigate this enzyme as a link between cellular metabolites, energy balance and fat accumulation.
What studies have found
Laboratory and mouse studies of NNMT inhibitors examined cellular metabolism and fat storage. A 2024 mouse study reported reduced weight and fat-mass gains, improved insulin sensitivity and changes in fatty-liver measures after 5-Amino-1MQ exposure.
These are preclinical findings in cells and mice. They do not establish human weight-loss efficacy or safety.
Read the research
Chemical reference
| Molecular formula | C10H11N2+ |
|---|---|
| Molar mass | Approximately 159.21 g/mol |
| Reference CAS | 685079-15-6 |
| PubChem CID | 950107 |
Reference values describe the positively charged 5-amino-1-methylquinolinium ion alone. They exclude its counterion; the complete salt formula and mass require confirmation of the supplied form.
Chemical information describes the named reference structure, not a batch analysis or confirmation of the material supplied. Counterions, water and excipients are excluded unless stated.
Understanding these details
A sequence describes the order of residues in a peptide. A molecular formula describes the atoms in the reference structure. Molar mass is expressed in grams per mole; it is not the amount in a vial. CAS numbers and PubChem identifiers help you find the corresponding chemical records.
Selected literature and reference information checked 11 September 2026. Study findings concern the preparations and models described; they do not certify this product. For laboratory research only.
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